CompletedEarly Phase 1

Intra-Articular Dexamethasone to Prevent Post-Traumatic Osteoarthritis: A Pilot Study

United States43 participantsStarted 2014-12

Plain-language summary

The primary aim of the study is to see if a single wrist injection (intra-articular) of dexamethasone at the time of treatment will reduce the incidence of early-onset of post traumatic osteoarthritis.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Unstable distal radius fracture
✓. Fracture type AO B1, B2, B3, C1, C2 or C3.
✓. 18-65 years old
✓. Understand and read English
✓. Community dwelling (not in assisted living or NH)

Exclusion criteria

✕. Open or bilateral DRF
✕. Associated upper extremity carpal fracture or carpal ligament injuries requiring casting or surgical repair at the time of DRF fixation.
✕. Greater than 2 weeks post injury
✕. Neurologic disorders affecting the hand, wrist or arm.
✕. History of permanent dementia, Alzheimer's or other neurologic dx
✕. Substance abuse
✕. Pathologic fractures
✕. Known pregnancy

What they're measuring

PTOA incidence

Timeframe: 3 years

Trial details

NCT IDNCT02318433

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-07-19

View on ClinicalTrials.gov More Distal Radius Fracture trials