UnknownNot Applicable

Study of Interventional Pulmonologic Treatment of Benign Central Airway Fibrotic Stricture

China160 participantsStarted 2014-12

Plain-language summary

The purpose of this study is to evaluate the efficacy and safety of four interventional pulmonology techniques for the treatment of fibrotic central airway stricture. The four techniques are： * balloon dilation * balloon dilation plus cryotherapy * balloon dilation plus spiculiform electrosurgery * balloon dilation plus mitomycin C injection

Who can participate

Age range

18 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * tracheal incision,intubation or bronchial tuberculosis caused central airway fibrotic stenosis * the degree of stenosis is above 50% * estimated survival duration is longer than 3 months * recieved no treatment one month before * can understand the statement informed consent * agree to enroll in the study Exclusion Criteria: * older than 70 years or younger than 18 years * not fibrotic stenosis * not central airway stenosis * existence of lumina collapse or twisting * severe arrhythmia, myocardial ischemia or hypertensive crisis * coagulation disorders * existence of severe organ disfunction * allergic to anesthesia drugs * refuse to participate the study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

percentage of the cases that got Ⅰand Ⅱlevel remission

Timeframe: 3 months

Trial details

NCT IDNCT02287389

SponsorTang-Du Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-12

Contact for this trial

Deguang Mu, PhD

86-29-84777825 deguang@fmmu.edu.cn

View on ClinicalTrials.gov More Obstructive Airway Disease trials