CompletedPhase 1

Use of Topical Lidocaine to Reduce Pain in Preterm Infants Receiving Nasal CPAP Continuous Positive Airway Pressure

Egypt60 participantsStarted 2013-10

Plain-language summary

The main purpose of this study is to evaluate the relative efficacy of topical lidocaine on reducing pain associated with the application of nasal CPAP in preterm infants

Who can participate

Age range28 Days

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Preterm infants \< 37 weeks gestation * Admitted to NICU, Mansoura University Children's Hospital * Respiratory distress requiring use of nasal CPAP * Informed consent obtained Exclusion Criteria: * Serious, life-threatening malformations * Use of sedation, analgesia in the preceding 72 hours * Those who undergo any surgical intervention * Those who undergo any painful procedures as venipuncture, intubation, suctioning, blood sampling, heel-prick, catheterization 30 minutes before assessment * Those with signs of nasal injuries at the time of application of nCPAP * Necrotizing enterocolitis

What they're measuring

The Premature Infant Pain (PIPP) Scale

Timeframe: Immediately after application of nasal CPAP (approx 5 min)

Trial details

NCT IDNCT02268968

SponsorMansoura University Children Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-12

View on ClinicalTrials.gov More Other Preterm Infants trials