CompletedNot Applicable

Analgesic Efficacy of Intravenous Ibuprofen in Biliary Colic

United States22 participantsStarted 2014-09-09

Plain-language summary

The aim of this study is to assess the analgesic efficacy of intravenous ibuprofen given in the Emergency Department for the treatment of biliary colic. We hypothesize that intravenous ibuprofen will provide a clinically significant drop in self-reported patient pain level as measured by the visual analog scale.

Who can participate

Age range

18 Years – 55 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients ages 18-55 * Present to ED with right upper quadrant (RUQ) abdominal pain * Suspected diagnosis of biliary colic * Negative pregnancy test for women of childbearing potential (complete POC testing form) * No history of cholecystectomy Exclusion Criteria: * Patient age \< 18 or \> 55 * Incarcerated * Hemodynamic instability * Inability to reliably self-report or communicate pain intensity and pain relief * Taking Warfarin * Cannot consent of are not competent to consent * Hepatic, renal, cardiac failure * NSAID or morphine allergy * History congenital bleeding diathesis or platelet dysfunction * Peptic ulcer diseases * Are otherwise unsuitable for the study in the opinion of the investigator/sub-investigators

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pain Score 120 Minutes After Study Medication Administration

Timeframe: 120 minutes post medication administration

Trial details

NCT IDNCT02268955

SponsorValleywise Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-06-21

Results submitted2018-01-29

View on ClinicalTrials.gov More Biliary Colic trials