CompletedNot Applicable

The Role of Perioperative Ventilation (Gas Exchange) During Intrabdominal Surgery on Cognitive Function

Russia109 participantsStarted 2012-10

Plain-language summary

Abdominal surgery commonly requires perioperative relaxation and therefore controlled mechanical ventilation. However, respiratory support can be associated with minor, yet clinically significant changes in blood gas content. The inadvertent hyperoxia (excessively high oxygen) and/or hypocapnia (excessively low carbon dioxide) can result in transient changes in cerebral blood flow and cognitive impair.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Informed consent * Age \> 18 years and below 80 yrs * Elective abdominal endoscopic intervention Exclusion Criteria: * Known cerebral disorder, incl. traumatic injury and severe vascular impairment * Known psychiatric illness * Severe drug or alcohol abuse * Resent stroke (during last 6 months) * Pregnancy * Within the 30 days prior to this study, either entry into any other randomized therapeutic study of an agent not licensed for the intended use or administration of any other investigational agent for the treatment of ALI. Patients must not participate in such studies for at least 30 days after enrolment into this study.

What they're measuring

Cognitive function

Timeframe: 36 hrs

Trial details

NCT IDNCT02267031

SponsorNorthern State Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-08

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