CompletedNot Applicable

A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterior Jaw

10 participantsStarted 2011-09

Plain-language summary

This study will involve placing donor bone into the back of lower jaw then covering with a newly designed titanium mesh. The mesh will then stay in the mouth for 4 months before it will be removed. Implants will be placed in the newly formed bone. The goal of this study is to test how well using a newly designed titanium mesh and bone particles can grow bone in the back of the lower jaw. The investigators are also checking if the newly formed bone will stay around implants that will have been in use for 12 months.

Who can participate

Age range18 Years – 99 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Systemically healthy patients (ASA I or II) * Non-smoker or light smokers (\< 10 cigarettes per day) * Good oral health (FMPS and FMBS \<20%) * At least two adjacent mandibular posterior teeth are missing * Inadequate vertical ridge height at edentulous region (less than 10mm) * Missing teeth for ≥ 3 months Exclusion Criteria: * Unstable and complicated systemic diseases or chronic disorders precluding surgical procedures * Systemic diseases with compromised healing potentials (Uncontrolled Diabetes Mellitus, HIV infections, etc.) * Bone disorders (Hyperparathyroidism, Osteoporosis, Paget's Disease) * Pregnant or expecting to become pregnant * Currently smoking (≥ 10 cigarettes/day) * Poor oral hygiene (≥20% Modified O'Leary Plaque Index) * Severe grinding, clenching, TMJ disorder * Untreated dental disease (periodontitis, caries, abscesses) in the research quadrant * Teeth exhibiting periapical pathology or purulence (symptomatic) in the research quadrant

What they're measuring

Bone Height

Timeframe: 5 months

Trial details

NCT IDNCT02255149

SponsorUniversity of Michigan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-11

Results submitted2016-03-17