A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterio… (NCT02255149) | Clinical Trial Compass
CompletedNot Applicable
A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterior Jaw
10 participantsStarted 2011-09
Plain-language summary
This study will involve placing donor bone into the back of lower jaw then covering with a newly designed titanium mesh. The mesh will then stay in the mouth for 4 months before it will be removed. Implants will be placed in the newly formed bone.
The goal of this study is to test how well using a newly designed titanium mesh and bone particles can grow bone in the back of the lower jaw. The investigators are also checking if the newly formed bone will stay around implants that will have been in use for 12 months.
Who can participate
Age range
18 Years – 99 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Systemically healthy patients (ASA I or II)
* Non-smoker or light smokers (\< 10 cigarettes per day)
* Good oral health (FMPS and FMBS \<20%)
* At least two adjacent mandibular posterior teeth are missing
* Inadequate vertical ridge height at edentulous region (less than 10mm)
* Missing teeth for ≥ 3 months
Exclusion Criteria:
* Unstable and complicated systemic diseases or chronic disorders precluding surgical procedures
* Systemic diseases with compromised healing potentials (Uncontrolled Diabetes Mellitus, HIV infections, etc.)
* Bone disorders (Hyperparathyroidism, Osteoporosis, Paget's Disease)
* Pregnant or expecting to become pregnant
* Currently smoking (≥ 10 cigarettes/day)
* Poor oral hygiene (≥20% Modified O'Leary Plaque Index)
* Severe grinding, clenching, TMJ disorder
* Untreated dental disease (periodontitis, caries, abscesses) in the research quadrant
* Teeth exhibiting periapical pathology or purulence (symptomatic) in the research quadrant
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.