Evaluation of the High Frequency Digit Triplet Test in Cystic Fibrosis

Inclusion criteria Work stream 1 * A diagnosis of CF, confirmed by genotype or sweat test, with characteristic clinical features. * Aged 11 years and over. * Informed consent. For age 11 to 18 years, consent will be sought from both the parent and young person (provided the young person is competent). Work stream 2 • As above but the participant has a pulmonary exacerbation (as defined by Fuch's criteria) requiring intravenous antibiotics. Work stream 3 * As for work stream 1, defined above. * CF patients aged 5-10 years * Healthy control children aged 5-10 years. * Informed consent from parent with assent from the child. Genetic Testing * Informed consent * Diagnosis of CF as above Exclusion criteria * None. In individuals with a hearing aid, we will perform PTA and HFDT tests without the aid. * Individuals found to have conductive deafness after randomisation will be fully assessed for this prior to continuing with the study.