UnknownPhase 3

Surgical Ablation of Long-standing Persistent AF During CABG

Russia116 participantsStarted 2014-12

Plain-language summary

Purpose. Comparison of outcomes in patients underwent CABG combined with left atrial and biatrial radiofrequency ablation of long-standing persistent atrial fibrillation. Hypothesis of the study - patients with long-standing persistent atrial fibrillation and coronary artery disease after CABG in combination with biatrial RFA have a better outcomes for the freedom of AF compared with patients undergoing left atrial RFA during CABG.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: * American College of Cardiology (ACC)/ American Heart Association (AHA) Indications for CABG * At least 2 ECG-verified (12-channel ECG, Holter telemetry) long-term persistent AF within last 12 months * The patient's consent to participate in the study Exclusion Criteria: * Intolerance of antiarrhythmic drugs * Heart valve disease requiring invasive treatment * Left atria more than 6.5 cm * Prior cardiac surgery * Active pacemaker treatment * Active anti-arrhythmic treatment (AAD) class I and III * Contraindication to oral anticoagulant/heparin treatment * Ejection fraction less than 30 % (EF \< 30 %) assessed by transthoracic echocardiography

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Freedom from atrial fibrillation

Timeframe: up to 36 months

Trial details

NCT IDNCT02246790

SponsorMeshalkin Research Institute of Pathology of Circulation

Sponsor typeNETWORK

Study typeINTERVENTIONAL

Primary completion2015-12

Contact for this trial

Sardor Rakhmonov

+79231278557 sardor5507@mail.ru

View on ClinicalTrials.gov More Coronary Artery Disease trials