CompletedPhase 3

Effects of 2 Different Duration of Albendazole Therapy in Patients With Neurocysticercosis in Brain ≤ 5 Lesions on CT

India97 participantsStarted 2014-03

Plain-language summary

Comparing the effect of two different duration of same drug albendazole in patients with Neurocysticercosis less than or equal to 5 lesions on CT head at the end of 6 months.

Who can participate

Age range2 Years – 18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 2-18 years. * Number of parenchymal lesions: upto 5\* * Stages of cysticerci at which albendazole treatment is effective * Vesicular stage * Colloid vesicular stage * Granular nodular stage Exclusion Criteria: * Cysticercotic encephalitis * Calcified cyst * Hydrocephalus * Intraventricular cyst * Subarachnoid cyst * Ophthalmic Cysticercosis * No of cysts \>5 * Known allergy to benzimidazole class of compound which includes anaphylaxis, hypotension, severe skin reactions . * Features of raised ICT (papilloedema, hyperventilation, hypertension, tonic posturing, B/L 6th nerve palsy, features of midline shift on CT/MRI) * Critically sick (respiratory failure, cardiovascular instability) * Already received albendazole or praziquantel or steroid therapy

What they're measuring

Number of cyst resolved/ calcified completely after therapy. Resolution or calcification of cyst assessed on CT head at the end of 6 months after starting albendazole

Timeframe: 1 year

Trial details

NCT IDNCT02243644

SponsorAll India Institute of Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-10

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