CompletedNot Applicable

Detection of Brown Adipose Tissue by Magnetic Resonance Imaging

United States8 participantsStarted 2015-01-20

Plain-language summary

The primary goal of this study is to assess the accuracy of conventional fat fraction proton MRI for the detection of Brown Adipose Tissue (BAT) in healthy subjects using \[18F\]-2-fluoro-2-deoxy-D-glucose (fluorodeoxyglucose) -PET as gold standard. In this pilot study, MRI and PET imaging of BAT of healthy adult volunteers will be performed on a combined PET/MRI scanner under mild cold condition.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Each subject must be fully informed and have signed consent. * BMI \< 34 * Normal neurological and psychological development / able to give consent * Willingness to participate in this study Exclusion Criteria: * Subjects less than 18 years of age * Severe claustrophobia * Women who are pregnant, nursing an infant or planning to become pregnant in the next 30 days * People who have a condition that makes MRI unsafe for them (for example, cardiac pacemaker, epicardial pacemaker leads, cochlear implants, metal aneurysm clip, iron filings in your eyes or metal halo devices) * Have had radiation therapy or chemotherapy in the 2 months prior to PET scan * Subjects are taking medications that may interfere with BAT detection

What they're measuring

Average dice similarity coefficient

Timeframe: Up to 1 year after the imaging scan

Trial details

NCT IDNCT02237872

SponsorUniversity of North Carolina, Chapel Hill

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2015-08-27

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