CompletedPhase 2

Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)

United States90 participantsStarted 2014-09

Plain-language summary

This study will test whether XAF5 (XOPH5) ointment, applied once daily to the lower eyelids for 10 weeks, reduces the prominence of lower eyelid fat in adults with moderate to severe steatoblepharon (excess eyelid fat).

Who can participate

Age range40 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria (abbreviated): * Moderate to severe lower eyelid steatoblepharon (LESS score of 2-4 bilaterally) * Men and women 40-70 years old * Healthy facial skin * Must understand and provide informed consent Exclusion Criteria (abbreviated): * Best corrected visual acuity worse than 20/40 in either eye * Regular use of ophthalmic medication in either eye * Planned use of contact lenses during the study * Any history of lower eyelid surgery

What they're measuring

Lower Eyelid Steatoblepharon Severity (LESS) Score--Clinician-Reported

Timeframe: 11 weeks

Trial details

NCT IDNCT02230761

SponsorTopokine Therapeutics, Inc.

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2014-12

Results submitted2015-11-19

View on ClinicalTrials.gov More Lower Eyelid Steatoblepharon (Excess Eyelid Fat) trials