TerminatedPhase 1/2

Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition

Stopped: Publication of guidelines advising against the use of ethanol locks.

United States39 participantsStarted 2014-07

Plain-language summary

This study is being implemented to identify the role of prophylactic use of ethanol lock in adult patients on home parenteral nutrition (HPN). Central catheter related blood stream infection is a major complication in patients on HPN. The investigators hypothesize that the prophylactic use of ELT will decrease the number of catheter related blood stream infections compared to the control group. The investigators further hypothesize that with the introduction of prophylactic ELT, the number of infections will decrease.

Who can participate

Age range18 Years – 90 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Newly started on Home parenteral Nutrition and anticipated duration \>3 months. * Not previously on Home Parenteral Nutrition. * Providing consent. * Patients with non-medicare insurance. * Patients with medicare insurance and a supplementary insurance. * Patients with single lumen Hickman® catheters. * No known alcohol addiction. Exclusion Criteria: * Failure to provide consent * Patients with medicare insurance and no other supplemental private insurance * Patients with a catheter type other than a single lumen Hickman® * Patients who are on HPN for less than three months * Pregnant patients * Patients who have previous proven addiction and dependence to alcohol. * Patients lacking capacity to provide consent * Patients who are not be managed by HPN team at investigator's institution

What they're measuring

Number of Catheter-Related Blood Stream Infections

Timeframe: 1 year

Trial details

NCT IDNCT02227329

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-10

Results submitted2017-08-07