CompletedNot Applicable

Multi-center Study of Residual Neuromuscular Block Incidence in the Post-anesthesia Care Unit

Spain763 participantsStarted 2014-06

Plain-language summary

Residual neuromuscular block (RNMB) is frequent in the immediate postoperative period and is a source of complications, mainly respiratory. The incidence is variable due to multiple factors. In Spain the incidence is unknown. The investigators hypothesize that a number of patients in the postanesthesia care unit (PACU) present with RNMB after general anesthesia using intermediate action neuromuscular block agents (NMBA). The main objective is to know the incidence of RNMB in Spanish hospitals. Secondary objectives are to observe the possible relationship with other pre- and intraoperative factors.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients \>18 years-old * General anesthesia with non-depolarizing NMBA * Transferred extubated on spontaneous ventilation to the PACU Exclusion Criteria: * American Society of Anesthesiologists physical status IV-V * emergency and cardiac surgery * patients unable to respond adequately at the moment of pre- or postoperative evaluation (psychiatric diseases, excessive somnolence, agitation, etc.) * noncompensated diabetes mellitus or diabetic neuropathy * symptomatic severe hypothyroidism (or untreated), or scheduled for total thyroidectomy * chronic or acute renal insufficiency * severe hepatopathy (Child-Pugh B, C) * intraoperative blood transfusion \>3 blood units * intraoperative maintained arterial hypotension * arrival to the PACU intubated or with instrumented airway (including surgical) * pre- or perioperative drugs intake affecting the neuromuscular transmission * neuromuscular diseases affecting the physiology of the neuromuscular system

What they're measuring

Residual neuromuscular block incidence (TOFr<0.9) measured by accelerometry in the PACU

Timeframe: Upon arrival to the PACU. Single evaluation.

Trial details

NCT IDNCT02226809

SponsorUniversity of Valencia

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2014-07