CompletedNot Applicable

TMS Augmented Exposure Therapy

Germany47 participantsStarted 2014-08

Plain-language summary

This study investigates the beneficial effects of prefrontal brain stimulation (with a facilitating TMS protocol) before exposure therapy in acrophobic patients. The two exposure sessions were realized in virtual reality. Before and after therapy, the phobic symptoms were measured on a subjective, behavioral and physiological level. The placebo-controlled single blinded study includes 50 phobic patients, which were randomized into verum or sham TMS.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Criteria for a simple phobia: specific heights Exclusion Criteria: Objective tinnitus Involvement in psychiatric treatments Clinically relevant psychiatric comorbidity Clinically relevant unstable internal or neurological comorbidity History of or evidence of significant brain malformation or neoplasm, head injury Cerebral vascular events Neurodegenerative disorder affecting the brain or prior brain surgery Metal objects in and around body that can not be removed Pregnancy Alcohol or drug abuse history of seizures

What they're measuring

Subjective Anxiety Symptoms

Timeframe: 4 weeks

Subjective Anxiety in Height Situation (BAT), Differences From Pre (Baseline) to Post Therapy (Week 4)

Timeframe: 4 weeks

Trial details

NCT IDNCT02223767

SponsorWuerzburg University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-04

Results submitted2022-08-30

View on ClinicalTrials.gov More Phobia trials