Study of the Efficacy and Tolerability of Intravitreal Injections of Ranibizumab Compared to Intravitreal Injections of Ranibizumab Combined With Targeted Retinal Photocoagulation to Treat Radiation Retinopathy.

Inclusion Criteria Subjects will be eligible to participate if the following criteria are met: * Ability to provide written informed consent and comply with study assessments for the full duration of the study * Age \> 18 years * Active radiation retinopathy resulting from any form of radiation treatment performed within the last 3 years. Radiation retinopathy is defined as any of the following: retinal hemorrhages, exudates, edema, and/or neovascularization, not attributable to other causes. * Best Corrected Visual Acuity (BCVA) of 20/25-20/400 in the study eye Exclusion Criteria Subjects who meet any of the following criteria will be excluded from this study: * Pregnancy (verified by positive pregnancy test) or lactation * Premenopausal women not using adequate methods of contraception. The following are considered effective means of contraception: surgical sterilization, use of oral contraceptives, barrier contraception with either a condom or diaphragm in conjunction with spermicidal gel, an intrauterine device (IUD), or contraceptive hormone implant or patch. * Any other condition that the investigator believes would pose a significant hazard to the subject if the investigational therapy were initiated. * Participation in any other simultaneous medical investigation or trial * Previous participation in any studies involving investigational drugs within 30 days before Day 0 (excluding vitamins and minerals). * History of allergy fluorescein, not amenable to treatment…