CompletedNot Applicable

Echocardiographic Evaluation of the Change on Pulmonary Blood Flow and Cardiac Function Induced by Capnothorax During One Lung Ventilation

25 participantsStarted 2014-08

Plain-language summary

Video-assisted thoracoscopic extended thymectomy (VATET) is a minimally-invasive method for excision of mediastinal mass instead of open thymectomy. The iatrogenic capnothorax with one-lung ventilation during VATET may cause hemodynamic instability due to the compression of intrathoracic structures. The purpose of this study is to evaluate the effects of capnothorax on the pulmonary blood flow and cardiac function during the VATET by using the transesophageal echocardiography.

Who can participate

Age range20 Years – 80 Years

SexALL

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Inclusion criteria

✓. Above 20 years of age.
✓. American Society of Anesthesiologists (ASA) Physical Status I, II, III.
✓. Thoracic surgical procedure (video-assisted thoracoscopic extended thymectomy )

Exclusion criteria

✕. Severe functional liver or kidney disease
✕. Diagnosed HF ( NYHA class \>3)
✕. Arrhythmia or received treatment with antiarrhythmic drug .
✕. Exceed BMI \> 30 kg/ m2
✕. COPD
✕. Pathologic esophageal lesion (esophageal stricture or varix )
✕. Pregnancy

What they're measuring

The changes of the echocardiographic indices

Timeframe: four time points during the operation. (1)10 min after induction (baseline); (2) 1 min after CO2 insufflation; (3)10 min after of CO2 insufflation; and (4)20 min after CO2 insufflation

Trial details

NCT IDNCT02220231

SponsorYonsei University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-03

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