CompletedNot Applicable

Nociceptive Gain Processing After Physical Therapy in Carpal Tunnel Syndrome

Spain100 participantsStarted 2014-08

Plain-language summary

This randomized clinical trial will investigate changes in pain intensity and nociceptive gain processing after the application of either physical therapy or surgery in women with carpal tunnel syndrome (CTS). The purpose of this study will be to determine changes in pain intensity, widespread pressure pain sensitivity and segmental thermal changes after the application of a physical therapy program based on desensitization maneuvers of the central nervous system or endoscopic surgery in women with CTS at medium and long-term follow-up periods. We hypothesize that the physical therapy intervention targeted to desensitization of the central nervous system is more effective than surgical intervention for modulating altered nociceptive gain processing in women with CTS.

Who can participate

Age range18 Years – 65 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * pain and paresthesia in the median nerve distribution * increasing symptoms during the night, * positive Tinel sign, * positive Phalen sign, * symptoms had to have persisted for at least 6 months * deficits of sensory and motor median nerve conduction according to guidelines of the American Association of Electrodiagnosis, American Academy of Neurology, and the American Physical Medicine and Rehabilitation Academy Exclusion Criteria: * any sensory/motor deficit related to the ulnar or radial nerve; * older than 65 years of age; * previous surgical intervention or steroid injections; * multiple diagnoses of the upper extremity (eg, cervical radiculopathy); * history of neck, shoulder, or upper limb trauma (whiplash); * history of a systemic disease causing CTS (eg, diabetes mellitus or thyroid disease); * history of other medical conditions (eg, rheumatoid arthritis, fibromyalgia); * pregnancy

What they're measuring

Changes in widespread pressure pain thresholds between baseline and follow-up periods

Timeframe: Baseline and 3, 6, 9 and 12 months after the intervention.

Trial details

NCT IDNCT02219919

SponsorUniversidad Rey Juan Carlos

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-05