Botulinum Toxin A to Treat Arm Tremor

Main Inclusion Criteria: * Diagnosis of 'definite essential tremor' in accordance with modified TRIG criteria, as follows: * Bilateral postural tremor with or without kinetic tremor, involving hands and forearms, that is visible and persistent. * It is to be noted that: * Tremor of other body parts may be present in addition to upper limb tremor. * Bilateral tremor may be asymmetric. * Tremor is reported by patient to be persistent, although the amplitude may fluctuate. * First onset of essential tremor at least 6 months before screening with stability of the tremor symptoms over 4 weeks and in the opinion of the investigator definite diagnosis of essential tremor. * Moderate-to-marked upper-limb postural and/or kinetic tremor at wrist level, corresponding to Fahn-Tolosa-Marin upper-limb tremor rating of at least 2 categories (scale part C, items 16-23) in the limb to be treated between of 2 or higher. * Visible tremor at wrist level in at least one of the four positions/tasks used in kinematic assessments * Tremor deemed by the investigator to require a treatment with 30 - 200 U NT 201 for a treatment of up to three joints of the selected upper limb (wrist treatment mandatory). * Stable concomitant anti-tremor medication and no clinically relevant findings in routine laboratory examinations. Main Exclusion Criteria: * Any neurological signs abnormal for the subject's age, other than the tremor itself and Froment's maneuver. * Exposure to the following tremoroge…