CompletedNot Applicable

Comparison Rectal Endoscopic Submucosal Dissection to Endoscopic Mucosal Resection

Australia300 participantsStarted 2014-07

Plain-language summary

The investigators have recently become proficient in a new, and we believe more effective technique for polyp removal. Known as Endoscopic Submucosal Dissection (ESD). ESD involves removing the polyp in one piece. It is preferable to remove the polyp in one piece as it minimises the chance of leaving residual polyp tissue behind. There have also been recent studies overseas that have shown this new technique to be quite effective. In this study, half of the patients will receive the newly developed technique of polyp removal (ESD), while the other half will receive conventional Endoscopic Mucosal Resection (EMR) treatment. This study will allow us to show which technique results in lower recurrence rates and is more effective.

Who can participate

Age range18 Years – 99 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Can give informed consent to trial participation * Lesion size 20 mm to 50 mm * Laterally spreading or sessile polyp morphology Exclusion Criteria: * Previous resection or attempted resection of target adenoma lesion * Endoscopic appearance of invasive malignancy * Age less than 18 years * Pregnancy * Active Inflammatory colonic conditions (e.g. inflammatory bowel disease) * Use of anticoagulant or antiplatelet agents other than aspirin less than 5 days prior to procedure * American Society of Anesthesiology (ASA) Grade IV-V

What they're measuring

Recurrence

Timeframe: 18 months

Trial details

NCT IDNCT02198729

SponsorProfessor Michael Bourke

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-05

View on ClinicalTrials.gov More Colonic Polyps trials