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Prospective Randomized Study: Assessment of PRF Efficacy in Prevention of Jaw Osteonecrosis After Tooth Extraction

Belgium100 participantsStarted 2014-01

Plain-language summary

This prospective study will include patients taking or having taken bisphosphonates and needing dental extractions. The aim of this study is to validate the contribution of PRF (Platelet Rich Fibrin) in tooth extraction sites. In the test group (PRF) and in the control group (no PRF), we use the same atraumatic extraction protocol associated with the same antibiotic procedure.

Who can participate

Age range50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients taking bisphosphonates whatever the indication, the type, the administration and the duration of treatment (we include patients taking or having taken bisphosphonates, even several years ago) * And who need tooth extraction (not recoverable in conservative dentistry and symptomatic tooth: dental and periodontal infections, symptomatic traumatic tooth fracture). Exclusion Criteria: * pregnant women * younger than 50 years old * jaw's radiotherapy * history of jaw osteonecrosis * jaw metastasis from an other cancer

What they're measuring

Number of jaw osteonecrosis after tooth extraction

Timeframe: 1year

Trial details

NCT IDNCT02198001

SponsorCliniques universitaires Saint-Luc- Université Catholique de Louvain

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-01

Contact for this trial

Dorothée L Deneubourg, MD, DDS

003227645702 dorothee.deneubourg@uclouvain.be

View on ClinicalTrials.gov More Bisphosphonate-Associated Osteonecrosis of the Jaw trials