CompletedNot Applicable

The Selection Criteria for the Second-look Endoscopy Among Patients With Bleeding Peptic Ulcers

Taiwan316 participantsStarted 2011-08

Plain-language summary

The purpose of this prospective study is to identify risk factors which could predict poor fading of SRH or early recurrent bleeding of peptic ulcer hemorrhage after successful endoscopic hemostasis and high-dose PPI infusion. These risk factors will be the selection criteria for patients who are indicated to receive second-look endoscopy.

Who can participate

Age range20 Years – 95 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Bleeding peptic ulcers with major stigmata of recent hemorrhage * All of these major SRH are treated by local injection of diluted epinephrine 1:10000 with or without combined therapy with a heater probe, argon plasma coagulation, band ligation, or hemoclip therapy Exclusion Criteria: * Bleeding due to tumor or cancer * Bleeding due to the presence of a Dieulafoy lesion * Ulcer bleeding due to mechanical factors (i.e., gastrostomy tube induction) * Proton pump inhibitors use within one week before enrollment * Failure to establish hemostasis under gastroscopy * Hypersensitivity to esomeprazole, pantoprazole, or any component of the formulation * Previously participated in the study

What they're measuring

the fading rate of major stigmata of recent hemorrhage

Timeframe: within 3 days after the index gastroscopy

Trial details

NCT IDNCT02197039

SponsorNational Cheng-Kung University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2014-07

View on ClinicalTrials.gov More Peptic Ulcer Hemorrhage trials