CompletedPhase 4

Clinical Study of Pain Reduction by Peri-arthroscopic PRP Application in Knee Degeneration

Germany58 participantsStarted 2010-07

Plain-language summary

The purpose of this study is to investigate reduction of pain, gain of function and improvement of life quality by intraoperative applied platelet- rich- plasma ( PRP ) during knee arthroscopy for degeneration and osteoarthritis OA by conducting a randomized- controlled, double-blinded trial ( RCT ) including 58 patients with a follow up of 12 months and pain, assessed by Visual- Analogue Scale (VAS) after 6 months as primary endpoint.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

inclusion Criteria: * degenerative knee pain * age: \> 18 years * informed consent * none to moderate comorbidity * arthroscopy under general anaesthesia indicated exclusion Criteria: * trauma of the knee within the last 6 weeks before surgery * circumscribed cartilage lesion with possibility of repair microfracture or autologous chondrocyte transplantation - procedures * contraindications against PRP. application * malignancies * severe comorbidities * age \<18 years * physically or mentally not able to provide informed consent * severe knee instability * corticosteroid injections within the last 6 weeks before surgery

What they're measuring

pain ( VAS )

Timeframe: 6 months

Trial details

NCT IDNCT02189408

SponsorRuhr University of Bochum

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-12

View on ClinicalTrials.gov More Knee Osteoarthritis trials