Autograft of Human Ovarian Tissue : Efficiency and Safety (NCT02184806) | Clinical Trial Compass
UnknownNot Applicable
Autograft of Human Ovarian Tissue : Efficiency and Safety
France40 participantsStarted 2010-06
Plain-language summary
Ovarian tissue cryopreservation is a new technique for female fertility preservation. One way to restore fertility is autotransplantation of ovarian tissue.
The principal purpose of this study will be to evaluate the efficiency and safety of this procedure.
Who can participate
Age range
18 Years – 45 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria :
* adult women (age ≥ 18 years old) who stored ovarian fragments before gonadotoxic treatments
* Women who desire to conceive
* Married women or in stable couple
* Cured women or in remission
* Women suffering of Premature ovarian failure
* Consenting women
* women with health insurance
Exclusion criteria :
* age \< 18 years
* women with normal ovarian function
* women with a disease at high risk for ovarian metastasis
* women with contraindication for surgery
* women with contraindication for pregnancy
* not cured women or not in remission
* women without health insurance
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Biological (FSH, LH, E2 and AMH) changes from graft until the revovery of ovarian function
Timeframe: every month after graft, up to 18 months
2
Radiological (ultrasonography and MRI) changes in ovarian imaging from graft until the revovery of ovarian function
Timeframe: every month after graft, up to 18 months