Active — Not RecruitingNot Applicable

LASER Trial. LAparoscopic Elective Sigmoid Resection Following divERticulitis - a Multicenter, Prospective, Randomized Clinical Trial

Finland133 participantsStarted 2014-09

Plain-language summary

The purpose of this study is to find out whether elective sigmoid resection will improve quality of life compared to conservative treatment with lifestyle guidance and fiber supplement in patients with a recurrent or complicated diverticulitis.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Recurrent left colon diverticulitis (minimum 3 within 2 years, at least 1 confirmed with CT) OR * Earlier complicated left colon diverticulitis OR * Prolonged (over 3 months) pain or disturbance in bowel habits after a CT-confirmed left colon diverticulitis Exclusion Criteria: * Multimorbidity that prevents elective surgery * Contraindication to laparoscopy * Colonic stricture * Fistula (e.g. colocutaneous, colovaginal, colovesical) * Active malignancy * Earlier resection of sigmoid colon or rectum * Acute diverticulitis that has not settled * Colonoscopy/sigmoidoscopy/virtual colonoscopy not performed within 2 years * Age \< 18 or \> 75 years * Pregnancy * Inability to answer health surveys (e.g. dementia, psychiatric condition)

What they're measuring

Gastrointestinal quality of life-index change at 6 months

Timeframe: 6 months from randomization

Trial details

NCT IDNCT02174926

SponsorHelsinki University Central Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-04

View on ClinicalTrials.gov More Diverticulum trials