TerminatedNot Applicable

Olfactory Function Following Endoscopic Endonasal Skull Base Surgery

Stopped: Per PI request upon data analysis limitation discovery.

United States50 participantsStarted 2014-06

Plain-language summary

The purpose of this study is to compare a subject's sense of smell before and after endoscopic endonasal surgery to remove a skull base abnormality (i.e. tumor, inflammatory process, fracture, defect, etc.) and use the information collected to validate approaches to surgery that will minimize side effects to the sense of smell function. Data will be collected using a smell identification test along with two questionnaires. In addition, demographic, medical history, treatment, outcome, and follow-up information will be collected.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients presenting with skull base pathologies requiring endonasal surgery at The Ohio State University Wexner Medical Center * 18 years or older * Able to consent for self * Negative serum pregnancy test for women of childbearing potential Exclusion Criteria: * Patient unable to return to clinic at specific follow-up times * Pregnant or nursing * Prisoners

What they're measuring

Changes in UPSIT Score for the Two Groups Undergoing Endoscopic Endonasal Surgery With or Without Flap

Timeframe: up to 12 months post surgery

Trial details

NCT IDNCT02165969

SponsorRicardo L. Carrau, MD

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-10-25

Results submitted2018-03-07

View on ClinicalTrials.gov More Skull Base Pathology trials