CompletedNot Applicable

Assessments of Dietary Restrictions in Young and Elderly Obese Men : Metabolism Obesity Nutrition Age

France71 participantsStarted 2014-05

Plain-language summary

The prevalence of obesity is growing in elderly with heavy consequences in term of medical complications and mortality, so that this is nowadays an important public health issue. The major therapeutic solution is dietary restrictions, but and the advantages and the metabolic consequences are not well known in elderly. The MONA study main aim is to assess the metabolic changes in this population, after dietary restrictions, compared to young people.

Who can participate

Age range30 Years – 70 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 30 \< years old \< 40 OR 60 \< years old \< 70 * obesity : 30 \< BMI \< 40 * stable blood pressure (diastolic \<90mmHg, systolic \< 140mmHg) * glycemia \< 1,26g/L, LDL cholest \<1,9-1,6g/L, Triglycerides \<2,5g/L * risk factors concerning high blood pressure, diabetes and dyslipidemia under control Exclusion Criteria: * Insulin dependent diabetes, non-insulin dependent diabetes * high blood pressure * dyslipidemia * history of cardiovascular diseases or bariatric surgery * undernutrition * HbA1C \>7% * non authorized treatments : Glucagon-like peptide-1 agonists, * incapacity to do physical activity

What they're measuring

Lipolysis at resting and during physical activity test

Timeframe: Change after 8 weeks dietary restrictions

Trial details

NCT IDNCT02161926

SponsorUniversity Hospital, Toulouse

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-02

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