CompletedNot Applicable

Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries

United States97 participantsStarted 2014-07

Plain-language summary

This study is investigating whether changes in the shape and size of bodily muscles and spinal cord anatomy can influence recovery rates following a motor vehicle collision (MVC). The objective is to demonstrate that the presence of muscle and spinal cord degeneration and associated muscle weakness is the consequence of a mild MVC-related injury involving the cervical spinal cord.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Males and Females (18 - 65 years of age) * Individuals less than one week post MVA with a primary complaint of neck pain. * Able to give written informed consent and complete interviews in English Exclusion Criteria: * Individuals with a spinal fracture from the MVA, or spinal surgeries * History of one or more MVAs or previous diagnosis of cervical or lumbar radiculopathy * History of neurological disorders (e.g. Multiple Sclerosis, previous stroke, myelopathy), inflammatory diseases (e.g. Hepatitis, Systemic Lupus Erythematosus, Rheumatoid Arthritis or Osteoarthritis, Alzheimers, Ankylosing Spondylitis, Crohn's disease, Fibromyalgia) or metabolic disorders (e.g. Diabetes, hyper- and hypo-thyroidism) * Standard contraindications to MRI: claustrophobia, metallic implants, pacemaker and pregnancy.

What they're measuring

MRI to assess the changes in markers of altered cervical spinal cord physiology and muscle degeneration.

Timeframe: < 1 week; 2 weeks; 3 months; 1 year of MVC

Trial details

NCT IDNCT02157038

SponsorNorthwestern University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-05

View on ClinicalTrials.gov More Whiplash Associated Disorders trials