Assessment of Day-night Secretion of Progesterone and LH Across Puberty

Inclusion Criteria: * Early and late pubertal girls with normal androgens * Early and late pubertal girls with hyperandrogenemia * All subjects will be girls from pre-puberty (Stage 1 breast development and pubic hair growth but at least 7 years old) to 7 years post menarche. Exclusion Criteria: * Pregnancy * Inability to comprehend what will be done during the study or why it will be done * Hemoglobin \<11.5 g/dL for non-African American subjects; Hemoglobin \< 11.0 g/dL for African American subjects * Persistently abnormal sodium, potassium, or bicarbonate (i.e., confirmed on repeat) * Persistently elevated creatinine, hepatic transaminases, or alkaline phosphatase (i.e., confirmed on repeat) * Total bilirubin \> 1.5 times upper limit of normal (i.e., confirmed on repeat) * Significant history of cardiac or pulmonary dysfunction (e.g., known or suspected congestive heart failure; asthma requiring intermittent systemic corticosteroids; etc.) * Untreated hypo- or hyperthyroidism (reflected by persistently abnormal TSH values) * Total testosterone \> 200 ng/dl * Basal (follicular) 17-OHP \> 200 ng/ml (in girls without a previous diagnosis of congenital adrenal hyperplasia) * DHEA-S \> 800 mcg/dl * Elevation of prolactin \> 2 times upper limit of normal * Weight less than 25 kg