CompletedNot Applicable

Study on Anal Human Papillomavirus Infection and Anal Intraepithelial Neoplasia Among Men Who Have Sex With Men in Indonesia, Malaysia, and Thailand

Thailand430 participantsStarted 2013-02

Plain-language summary

OBJECTIVES 1. To determine the prevalence and incidence of anal HPV infection, including infection with high-risk HPV types, among MSM in Indonesia, Malaysia, and Thailand. 2. To study the prevalence and incidence of HGAIN among these MSM. 3. To evaluate risk factors, including HIV status, for anal high-risk HPV infection and HGAIN among these MSM. Study population An approximately 75 HIV-positive and 75 HIV-negative MSM who attended the study clinic in Kuala Lumpur, Jakarta, and Bangkok will be enrolled. The study will also enroll 185 HIV-positive and 95 HIV-negative MSM who are previous participants of the MSM VCT study. There will be approximately 260 HIV-positive and 170 HIV-negative MSM in total in this study.

Who can participate

Age range18 Years – 90 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Male with history of anal sex with men or previous participants of the MSM VCT study.
✓. Age 18 years old or older.
✓. Indonesian or Malaysian or Thai citizen as identified by the Indonesian or Malaysian or Thai National Identification card.
✓. Willing to provide location or contact information and allow contact.
✓. Available for follow-up for the planned study duration.
✓. Understand the study and sign informed consent form.

Exclusion criteria

✕. History of prior treatment for anal cancer OR had anal cytology or high-resolution anoscopy or infrared coagulation within 12 months prior to enrollment OR had trichloroacetic acid or podophyllin application of the intraanal area in the past month OR evidence of active concurrent intraanal or perianal bacterial or herpes simplex infection.
✕. Persons who have a history of a medical or psychiatric disorder by investigator's interview and physical examination according to standard practices, that in the judgment of the investigator(s), would interfere with ability to give informed consent.

What they're measuring

prevalence and incidence of anal HPV infection, including infection with high-risk HPV types, among MSM in Indonesia, Malaysia, and Thailand.

Timeframe: December 1,2014 (up to 2 years)

Trial details

NCT IDNCT02155231

SponsorThai Red Cross AIDS Research Centre

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-12

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