TerminatedNot Applicable

Impact of Exercise on Cognitive Impairment in End-Stage Renal Disease

Stopped: Funding has expired

United States20 participantsStarted 2014-05

Plain-language summary

The purpose of this study is to evaluate the impact of 12 weeks of exercise on cognition in patients with end stage renal disease.

Who can participate

Age range

20 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with ESRD on dialysis * Age greater than 20 years * Have means of transportation to and from the exercise session * Speak English (as the neuropsychological tests will be performed in English) Exclusion Criteria: * Recent myocardial infarction (within 6 weeks), unstable angina, uncontrolled arrhythmias, congestive heart failure (\> NYHA grade II) * History of stroke in the last 2 months * Active respiratory disease * Uncontrolled hypertension * Severe uncontrolled diabetes * Persistent predialysis hyperkalemia * Active decompensated liver disease * Symptomatic peripheral vascular disease * Musculoskeletal abnormalities that will be prohibit their participation in the exercise program * Health conditions needing frequent hospitalizations * Other health conditions causing inability to follow exercise program correctly * Unwillingness to participate in structured exercise program * Current use of antipsychotics or anti-epileptics * Inability to hear, read or write which will limit their ability to perform the cognitive tests

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Feasibility

Timeframe: Up to 26 Weeks

Trial details

NCT IDNCT02145702

SponsorUniversity of Kansas Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-12

View on ClinicalTrials.gov More Cognitive Impairment trials

Who can participate

Age range

20 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.