Restoring Masticatory Function to Treat Chronic Pain

Inclusion Criteria: * Completely dentate (except for the third molars; including if they were treated before enrollment by conventional or implant-supported fixed prosthesis allowing similar potential comfortable chewing on both sides) * Normal Angle Class I occlusion * Self-reported pain-intensity scores from 4 to 9 in a 0-10 visual analogue scale (VAS) or numerical pain rating scale (NRS). * Chronic (over 6 months) joint and/or muscle pain, according to diagnostic criteria for temporomandibular disorders (DC/TMD), for which they had requested therapy Exclusion Criteria: * Psychosis * Major depression * Substance abuse * Cognitive impairment * Addiction to morphine or derivates * Litigation or asking for disability/retirement compensation for chronic pain * Dental care professionals * Orthodontic therapy during the last 2 years * Patients with any pain that is more severe, in the same location as, or cannot be clearly distinguished from TMD pain * Individuals for whom minimally invasive occlusal adjustment could not achieve occlusal equilibration, including: Over 2 mm of difference between the maximal intercuspal position and the centric occlusion or over 4 mm of difference between upper and lower archs (or over 2mm on at less one side) measured: between the mesial fosses of first upper premolars with respect the buccal cusps of the first lower premolars; and/or between the mesiopalatal cusp of the first upper molars respect to the central (mesial) fossae of the first low…