CompletedPhase 4

The Laparotomy Study

Denmark128 participantsStarted 2014-09

Plain-language summary

The depth of neuromuscular blockade (NMB) during surgery may cause a clinical dilemma between optimal surgical conditions and the risk of postoperative residual blockade. The aim of the study is to investigate if intense NMB improves surgical conditions during operation in patients scheduled for elective open upper abdominal surgery.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients \> 18 years old * Elective open upper abdominal surgery * Can read and understand Danish * Informed consent Exclusion Criteria: * Known allergy to rocuronium or sugammadex * Severe renal disease, defined by S-creatinine\> 0.200 mmol/L, GFR \< 30ml/min or hemodialysis * Neuromuscular disease that may interfere with neuromuscular data * Abdominal mesh with size larger than 5\*5 cm * Lactating or pregnant

What they're measuring

Surgical Rating Score

Timeframe: After randomization every 30 minutes during the operation from first incision to last suture of fascial closure, up to 300 minutes

Trial details

NCT IDNCT02140593

SponsorHerlev Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-05

Results submitted2017-01-10

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