CompletedNot Applicable

The Efficacy and Safety of Ramosetron in Patients Undergoing Off Pump Coronary Artery Bypass Surgery

South Korea114 participantsStarted 2013-06

Plain-language summary

The purpose of this study is to assess the effects of ramosetron on corrected QT interval in patients undergoing off pump coronary artery bypass surgery.

Who can participate

Age range20 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Elective off-pump coronary artery bypass graft surgery Exclusion Criteria: * Emergency operation * preoperative use of any inotropics or mechanical assist device * severe liver disease (\>Child class II) * dialysis dependent renal failure * Left ventricular ejection fraction \<30 % * Combined major surgery like carotid endarterectomy * Previous allergy history to any 5-hydroxytryptamine type 3 (5-HT3) antagonist * Preoperative QT prolongation ( 500 \>msec) or arrhythmia

What they're measuring

corrected QT interval (QTc interval)

Timeframe: up to 240 minutes after induction of general anesthesia

Trial details

NCT IDNCT02139241

SponsorSeoul National University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-10

View on ClinicalTrials.gov More Coronary Artery Bypass Graft Triple Vessel trials