Next Science Wound Gel Efficacy in Chronic Wound Versus Standard of Care

Inclusion Criteria: * Male or female 18 years or older * Presence of full-thickness wound for more than one month (i.e. chronic) * Ulcer must be greater than 1 centimeter in area to enable biofilm sampling * NOT a candidate for vascular reconstructive surgery to restore blood flow to the wound * Willing to comply with all study procedures and be available for the duration of the study * Provide signed and dated informed consent Exclusion Criteria: * Subjects unable to provide signed and dated informed consent * Male or female less than 18 years old * Presence of a full-thickness wound for less than one month * A candidate for vascular reconstructive surgery to restore blood flow to the wound * Subjects with bleeding dyscrasia or with medical conditions that would make a bleeding complication likely * Subjects who's wound is less than 1 cm precluding adequate wound biofilm sampling * Subject with known allergic reaction to the study products