UnknownPhase 3

Targeting Monoaminergic Neuronal Networks in the Parkinsonian Patients After Carbon Monoxide Intoxication

Taiwan25 participantsStarted 2013-08

Plain-language summary

The study purpose is to determine the clinical values of 18F-FP-(+)-DTBZ in the diagnosis of Parkinsonism in patients with carbon monoxide intoxication, regional distribution and its correlation with clinical parameters. This study is expected to be completed in a period of 3 years.

Who can participate

Age range20 Years – 65 Years

SexALL

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Inclusion criteria

✓. Male or female age 20 years to 65 years.
✓. Patients group should fulfilled diagnostic criteria of carbon monoxide intoxication
✓. Patients who provide a written informed consent prior to study entry. If the patient is incapable of informed consent, the caregiver may consent on behalf of the patient (the patient must still confirm consent)

Exclusion criteria

✕. History of developmental disorders, agitated mood or a confused state that prevented either a neuropsychiatric interview or neuroimaging.
✕. Unable to stay still in the PET scanner for 30 minutes.
✕. History or presence of QTc prolongation. (\>500msec)
✕. Pregnancy and breast feeding.

What they're measuring

Assess the regional decline in 18F-DTBZ uptake of Parkinsonism after carbon monoxide intoxication

Timeframe: up to 3 years

Trial details

NCT IDNCT02138864

SponsorChang Gung Memorial Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-05

View on ClinicalTrials.gov More Carbon Monoxide-induced Parkinsonism trials