Topiramate Trial for Compulsive Buying (NCT02138058) | Clinical Trial Compass
CompletedPhase 2
Topiramate Trial for Compulsive Buying
Brazil42 participantsStarted 2015-01
Plain-language summary
It is a double blind controlled study to test the hypothesis that Topiramate is more effective than placebo in the treatment of compulsive buying, during a period of 12 weeks
Who can participate
Age range21 Years – 60 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Match criteria for compulsive buying, according to McElroy et al. (1994), confirmed by semi-structured interview modeled after the Schedules for clinical assessment in neuropsychiatry (SCID)
* woman within fertility age have to be already practicing an acceptable contraception method and to be negative at a pregnancy test
Exclusion Criteria:
* illiteracy
* pregnancy and breastfeeding for woman
* previous history of alcohol abuse/dependence with current elevation of liver enzymes, or a present diagnosis of alcohol abuse/dependence
* past or current drug abuse/dependence, except for nicotine
* history of current or past Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders diagnosis of bipolar disorder, schizophrenia, psychosis or any neuropsychiatric condition causing cognitive impairment
* a history of suicide attempt or acute suicide risk
* severe depression indicated by a score higher than 30 at the beck depression inventory
* current participation on psychotherapy or use of pharmacological agent or experimental dispositive for compulsive buying in the past 3 months
* current use of psychotropic drugs, except benzodiazepines
* cardiovascular disease including a history of heart attack, stroke, arrhythmia, cardiac failure in the past 5 years. Uncontrolled high blood pressure.
* chronic or acute renal or liver failure, as well as Retinopathy and thyroidopathy
* a personal or family history of nephrolithiasis
* immunodeficiency
* a…
What they're measuring
1
Yale-Brown Compulsive-Obsessive Scale Shopping Version