Comparator Study of the Effect of Glycopyrrolate and Glycopyrronium in Subjects With Axillary Hyperhidrosis

Inclusion Criteria: * Male or female, 18 years of age or older. * Primary, axillary hyperhidrosis of at least 6 months duration. * Hyperhidrosis Disease Severity Score (HDSS) of 3 or 4 at baseline. * For each axilla, a baseline gravimetric measurement of sweat production of at least 50 mg over 5 minutes, while at rest, at room temperature. * Male or non-pregnant, non-lactating females. Exclusion Criteria: * Current pregnancy or lactation. * Prior surgical procedure for hyperhidrosis. * Any prior axillary treatment with an anti-hyperhidrosis medical device * Any prior treatment with an investigational drug within 4 weeks prior to Baseline/Day 1 or within 5 elimination half lives of the active agent, whichever is longer or 6 weeks if the elimination half life is not known. Experimental devices are excluded without the approval of the Medical Monitor. * Prior treatment with botulinum toxin (e.g., Botox®) for axillary hyperhidrosis within 1 year of Baseline/Day 1. * Subjects with clinically significant abnormalities in laboratory values. * Subjects with a positive Hepatitis or HIV.Hepatitis B surface antibody positive is allowed only if the subject has a history of having received Hepatitis B vaccination and there are no clinically significant abnormalities in screening liver function tests. * Treatment with cholinergic, serotonergic antagonists, and dopamine partial agonists thought to relieve antidepressant-induced hyperhidrosis, within one month prior to Baseline/Day 1. * T…