CompletedNot Applicable

Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.

United States160 participantsStarted 2014-05

Plain-language summary

The purpose of this study is to determine the efficacy of a negative pressure wound therapy (NPWT) system after revision total knee and hip arthroplasty in patients at high risk for infection. It is hypothesized that the use of NPWT system (i.e., Prevena) in high risk patients prevents wound complications and decreases reoperation rates.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Scheduled revision Total Hip or Knee Arthroplasty Procedure * Presence of one of the following: body mass index (BMI) greater than 35, use of blood thinners other than acetylsalicylic acid (ASA) after surgery, peripheral vascular disease, depression, diabetes mellitus, current tobacco use, history of prior infection, current use of immunomodulators or steroids, current history of cancer or hematological malignancy, rheumatoid arthritis, renal failure or dialysis, malnutrition, liver disease, transplant status, or HIV. Exclusion Criteria: * Patient lives \>100 miles from hospital * Patient is \< 18 years old * Silver allergy

What they're measuring

Number of Patients With Wound Complications

Timeframe: Within 90 days after surgery

Re-operation Rates

Timeframe: Within 90 days after surgery

Readmission Rates

Timeframe: Within 90 days after surgery

Trial details

NCT IDNCT02127281

SponsorThe Cleveland Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-04-24

Results submitted2017-08-17

View on ClinicalTrials.gov More Prosthesis-related Infections trials