Pilot Tape Harvesting Study

Key Inclusion Criteria: * Healthy volunteers must be in good overall health as determined by the Investigator, based on medical history, physical examination (per standard dermatology practice), and vital signs. * Subjects with lupus must present with active DLE or SCLE skin disease (with or without systemic manifestations of SLE, as defined by ≥4 out of 11 classification criteria for SLE). * Subjects with AD must have been diagnosed by the Eichenfield revised criteria of Hanifin and Rajka, disease duration for at least 2 years before Screening and disease activity defined as Investigator's Global Assessment (IGA) score ≥3 at screening Key Exclusion Criteria: * History of severe allergic or anaphylactic reactions or history of allergic reactions likely to be exacerbated by tape harvesting (e.g., allergy to adhesives). * Other unspecified reasons that, in the opinion of the Investigator, make the subject unsuitable for enrollment. Key Exclusion Criteria for Healthy Volunteers * History of any clinically significant medical condition, as determined by the Investigator, that may impact study analyses Key Exclusion Criteria for Subjects with Discoid or Subacute Cutaneous Lupus: * Evidence of skin conditions other than DLE or SCLE at the Day 1 Visit that, in the opinion of the Investigator, would interfere with the study execution or analysis. * History of malignancy in the last 5 years (nonmelanoma skin cancer that is considered cured by the Investigator will not be exclus…