The Breast Duct: Pilot Study of Genomic Sequencing of Exfoliated Ductal Cells Obtained Through Endoscopy and Lavage

Inclusion Criteria: * Be female * Have at least one intact nipple * If over 50, have had a normal mammogram within 12 months prior to the enrollment date * Have a normal physical examination of the breast to be studied within 12 months prior to the enrollment date * Be \> 18 years of age * Sign the informed consent form Exclusion Criteria: * Be currently pregnant or pregnant within the last 12 months * Be currently lactating or lactated within the last 12 months * Have received chemotherapy in the last 12 months * Have had an abnormal mammogram within the last year * Have had any subareolar or other surgery (papilloma resections, biopsies or fine needle aspirations) within 2 centimeters of the nipple (biopsies and fine needle aspirations \>2 centimeters from the nipple are acceptable) * Have active infections or inflammation in a breast to be studied * Have a known allergy to lidocaine * Be unwilling to sign informed consent