Transcatheter Valve Implantation in Patients With Dysfunctional Left and Right Sided Heart Valves

Inclusion Criteria: * Patients will be considered eligible for transcatheter valve implantation if the risk of serious morbidity or mortality with surgical intervention is deemed to be greater than 10 percent by the treating cardiologist and consulting surgeon. The Melody Valve is intended for use in the following clinical conditions: * Existence of a full (circumferential) RVOT conduit that was equal to or greater than 16 mm in diameter when originally implanted, AND * Dysfunctional RVOT conduits with a clinical indication for intervention, AND EITHER * Regurgitation ≥ moderate * Stenosis: mean right ventricular outflow tract gradient ≥ 35 mmHg * The Edwards Sapien Valve will be used in the aortic position for valves and conduits larger than 23mm in diameter with a landing zone less than 26-27mm, otherwise the melody valve will be considered * The Edwards Sapien Vavle will also be considered in other positions that have an adequate landing zone and a large enough circumference * The Melody valve may be utilized outside of its approved indications for valve replacement in high risk surgical patients Exclusion Criteria: * There are no known contraindications for implantation of the Melody Valve or the Edwards Sapien Valve