A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures

Inclusion Criteria: * Subjects must have at least 10 teeth * Subjects must have the need for a dental extraction under general anesthesia (for behavioral reasons) * Subjects will be recruited regardless of the extent and severity of their dental and/or periodontal disease Exclusion Criteria: * Age under 18 years * Body weight under 40 kg * Receipt of antibiotics in the previous 3 months * Routine use of oral antiseptics * A history of allergy or intolerance to amoxicillin * A history of allergy or intolerance to chlorhexidine * A history of allergy or intolerance to amoxicillin-clavulanate * Any type of congenital or acquired immunodeficiency * Any known risk factor for bacterial endocarditis * Any known risk factor for prolonged bleeding