CompletedPhase 2

Comparison of Effect of Postoperative Cyclosporine A 2% Ophthalmic Emulsion and Betamethasone Eye Drop on Surgical Success of Trabeculectomy Procedure

Iran40 participantsStarted 2014-04

Plain-language summary

Glaucoma is one of the leading causes of blindness worldwide and trabeculectomy is the most commonly performed operation to slow-down the disease progression. In this study, we compare the effect of topical cyclosporine A and betamethasone eye drops on the postoperative course and surgical success of trabeculectomy.

Who can participate

Age range20 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * POAG patient with insufficient IOP control on maximal tolerable medical therapy (MTMT), undergoing primary trabeculectomy with MMC augmentation. Exclusion Criteria: * Age \<20 years * History of previous ocular surgery in the same eye; * Candidate for combined surgery; * Pregnancy; * Breast feeding; * Monocular subject; * Allergy to any topical antiglaucoma medication or cyclosporine

What they're measuring

Intraocular Pressure (IOP)

Timeframe: Up to 6 months after surgery

Bleb morphology

Timeframe: Up to 6 months after surgery

Subjective dry eye symptoms

Timeframe: Up to 6 months after surgery

Trial details

NCT IDNCT02114073

SponsorMashhad University of Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-11

View on ClinicalTrials.gov More Glaucoma, Open Angle trials