Verifying the Effectiveness of the NUsurface® System

Inclusion Criteria: * Had \> 6 months ago a medial partial meniscectomy as confirmed by patient history and MRI * Is between age 30 and 75 years (inclusive) at the time of study treatment * Has neutral alignment ±5º of the mechanical axis, as measured from the angle formed by a line drawn from the center of the femoral head to the medial tibial spine and a line drawn from the medial tibial spine and the center of the ankle joint * Has ≥ 2 mm intact medial meniscal rim capable of being fitted with a NUsurface® device AND is also recommended for the baseline non-surgical (and, if likely to receive benefit, any injection) therapies to be administered in the study. * Is willing to be entered into either arm of the study: implanted with the NUsurface device OR treated with the recommended control arm therapies. * Is willing and able to attend all follow up visits, complete all study questionnaires, and undergo required X-ray and MRI schedule * Is able and willing to understand and sign the Informed Consent Form * Is able to read and understand the English language * Has a KOOS Pain of ≤ 75 (100 being the highest attainable and no pain) Exclusion Criteria: * Has a symptomatic knee because of a tear that could be addressed by a repeat partial meniscectomy leaving \> 4 mm of medial meniscus rim * Has evidence of a Outerbridge Grade IV cartilage loss on the medial tibial plateau or femoral condyle that potentially could contact a NUsurface implant (e.g., a focal lesion \> 0.5 cm2 c…