Celecoxib in Preventing the Damaging Effects of Sunburn in Healthy Volunteers

Inclusion Criteria: * The subject as Fitzpatrick skin type I, II, or III * If the subject is female and of childbearing potential (women are considered not of childbearing potential if they are at least 2 years post-menopausal and/or surgically sterile): * Has been using adequate contraception (e.g., condom, intrauterine device \[IUD\], diaphragm and spermicide gel combination) since her last menses and will use adequate contraception during the study, AND * Is not lactating, AND * Has had a negative pregnancy test (serum or urine) within 14 days prior to the first dose of study medication * The subject is willing to abstain from the use of non-steroidal anti-inflammatory drugs (NSAIDs) for the duration of the study * The subject is willing to abstain from the use of all topical agents applied to the buttocks for the duration of the study * The subject is willing to participate for the duration of the study * The subject has provided written informed consent prior to administration of any study related procedures Exclusion Criteria: * The subject is currently taking any medication that may alter the sunlight response or cause an adverse reaction * The subject has a history of melanoma, lupus, psoriasis, rosacea, porphyria, photosensitivity disorder, keloid formation, connective tissue disorder, or any disease that would increase the risk associated with study participation * The subject has excessive hair, blemishes, nevi, uneven pigmentation, sunburn or suntan on t…