Haldol/Diphenhydramine Versus Metoclopramide/Diphenhydramine for Treatment of Acute Headache in the ED: A RCT

Inclusion Criteria: Migraine Headache must contain the following: * At least two: Unilateral, Throbbing, Worsening with activity, Moderate to severe pain * At least one: Nausea or Vomiting, Photophobia or phonophobia * Ages 18-50 Exclusion Criteria: * Hypersensitivity to haloperidol, metoclopramide, and/or diphenydramine * History of ischemic heart disease or signs or symptoms of ischemic heart disease * History of stroke or transient ischemic attack (TIA) * History of peripheral vascular disease * History of uncontrolled hypertension with presenting diastolic blood pressure \> 100 * Use of an ergotamine derivatives, triptan, or dopamine-blocking anti-emetic within the past 24 hrs * Concurrent administration or within 2 weeks of discontinuing an MAO inhibitor * Concurrent management of hemiplegic or basilar migraine or known neurologic disorder * Severe hepatic impairment * Pregnancy or breastfeeding * History of cancer (except non-melanoma skin cancer) * Previous involvement in the study * Febrile to 100.5 or greater * Any indication for further diagnostic evaluation of this headache such as a lumbar puncture or CT scan. * Headache differs from their normal headache