CompletedPhase 4

Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency Setting

France194 participantsStarted 2013-08-02

Plain-language summary

Intranasal (IN) administration of opiates is an appealing non-invasive way of treating acute traumatic pain in prehospital and Emergency departments (ED). The investigators hypothesize that IN administration of Sufentanil is equal as compared with Intra veinous (IV) administration of Morphine wich is widely recommended in ED. The investigators study is a multicentric, comparative, randomized, double-blind, double-placebo study, comparing quality of analgesia in both groups 30 minutes after first administration of opiates. The investigators also asses side effects and patient satisfaction in both groups.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Traumatic pain * Numeric Pain Rating Scale (NPRS) \>5 /10 * Age between 18 and 75 years old Exclusion Criteria: * Medical pain (headache, chest pain,...) * Respiratory, renal or hepatic insufficiency * Drug addiction * Medical or Chirurgical sinus history * Oxygene saturation \< 90% * Systolic blood pressure \< 90mmHg * Head injury with a neurological Glasgow Coma Scale (GCS) \< 14 * Opioid allergy * Facial traumatism * Patient unable do understand or assessing NPRS * Opiates administration within 6 hours before admission

What they're measuring

Efficiency of Analgesia

Timeframe: 30 minutes

Trial details

NCT IDNCT02095366

SponsorUniversity Hospital, Grenoble

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-04-10

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