By InvitationNot Applicable

Biomarker Levels During Indwelling Pleural cAtheter Sample Testing

United States95 participantsStarted 2014-01

Plain-language summary

Some patients that have a tunneled pleural catheter will not have the pleural fluid (water around the lung) return after some time (pleurodesis). The purpose of this study is to understand how the investigators can predict who will achieve pleurodesis and how this occurs by studying the pleural effusion.

Who can participate

Age range18 Years – 99 Years

SexALL

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Inclusion criteria

✓. Malignant effusion confirmed by cytology or pleural biopsy
✓. exudative effusion in the setting of known malignancy with no other identifiable cause
✓. Malignant effusion due to tumors that are historically rapidly responsive to systemic therapy (small cell lung cancer, hematological malignancies) will only be included if refractory to standard chemotherapy

What they're measuring

To determine the median time to pleurodesis

Timeframe: 12 week follow up

Trial details

NCT IDNCT02092155

SponsorJohns Hopkins University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12

View on ClinicalTrials.gov More Malignant Pleural Effusions trials