Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery (NCT02084927) | Clinical Trial Compass
UnknownPhase 1
Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery
Israel62 participantsStarted 2014-04
Plain-language summary
The aim of the current study is to evaluate, in a prospective cross-over, randomized study, the effect of hyperbaric oxygen therapy (HBOT) on patients with chronic neurological deficits and cognitive impairment after anterior skull base meningioma tumor removal.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Post intracranial meningioma removal surgery 3-12 months prior to the inclusion in the study.
* All patients have to have persistent cognitive or neurological complaints regarding without noticeable improvement during the last month prior to their enrolment.
* Age 18 years or older.
Exclusion Criteria:
* Dynamic neurologic/cognitive improvement or worsening during the past month;
* Evidence of dynamic cognitive/neurological improvement in the last month.
* Previous brain radiotherapy and/or radiosurgery.
* Steroids dependence
* Seizures 1 month previous to inclusion
* Had been treated with HBOT for any other reason 1 month prior to inclusion;
* Have any other indication for HBOT;
* Chest pathology incompatible with pressure changes;
* Inner ear disease;
* Patients suffering from claustrophobia;
* Inability to sign written informed consent;
* Smoking patients will not be allowed to smoke during the study and if they would not comply with this demand they will be excluded.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.