CompletedPhase 2/3

Comparison Between Rectal & Sublingual Misoprostol Before Caesarian Section To Reduce Intra & Post-Operative Blood Loss

Egypt636 participantsStarted 2013-02

Plain-language summary

The aim of the work is to evaluate \& compare the effectiveness of rectally administered PGE1 synthetic analogue (misoprostol) 400 microgram versus sublingually administered misoprostol before caesarean section to decrease blood loss during and after the operation.

Who can participate

Age range18 Years – 38 Years

SexFEMALE

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Inclusion criteria

✓. Patients booked for elective cesarean section.
✓. Singleton pregnancies. 3- Full term pregnancies (GA 37-42 weeks). 4- Patients with only previous one cesarian section

Exclusion criteria

✕. Primigravida.
✕. Blood dyscrasias.
✕. Large fibroids.
✕. Multiple pregnancies.
✕. Overdistended uterus eg. Hydramnios.
✕. Pre-eclampsia.
✕. Marked maternal anemia (Preoperative hemoglobin \< 9 gm/dl).
✕. Previous history of PPH.

What they're measuring

Intraoperative Blood Loss

Timeframe: from start of cesarean section till the end of operation (average one hour)

Trial details

NCT IDNCT02083107

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-02

Results submitted2014-04-24

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